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In two starts against the New York Yankees this year, Jon Lester is 2-0 with 12 strikeouts and a 5.25 ERA. Bartolo Colon gave up just two runs in six innings in his lone start against Boston on May 13.
Both get the start for their respective clubs on Friday night at Fenway Park, as the Sox and Yankees open up a three-game series.
Adrian Gonzalez started the scoring for the Red Sox the last time they faced Colon with a two-run home run in the fourth. He'll start at first and bat third Friday.
Kevin Youkilis added a two-run homer of his own during that game. He'll bat cleanup and play third.
Derek Jeter leads things off for the Bronx Bombers. Jeter has three RBIs in six games against Boston this season. Robinson Cano gets the start at second and will bat cleanup.
Jarrod Saltalamacchia will be behind the plate and bat seventh after a night off on Thursday. Josh Reddick gets the start in right field, a game after blasting his fifth home run of the season.
Here's the rest of Friday's lineups.
Red Sox
Jacoby Ellsbury. CF
Dustin Pedroia, 2B
Adrian Gonzalez, 1B
Kevin Youkilis, 3B
David Ortiz, DH
Carl Crawford, LF
Jarrod Saltalamacchia, C
Josh Reddick, RF
Marco Scutaro, SS
Yankees
Derek Jeter, SS
Curtis Granderson, CF
Mark Teixeira, 1B
Robinson Cano, 2B
Nick Swisher, RF
Andruw Jones, LF
Russell Martin, C
Jorge Posada, DH
Eduardo Nunez, 3B