That's the decision facing the Indianapolis Colts right now, as they have to choose between keeping Peyton Manning or drafting Stanford quarterback Andrew Luck.
They could keep Manning and draft Luck, of course, but the 22-year-old signal-caller is by all accounts ready to step in and play right away. Keeping him on the bench behind Manning would be a waste of talent.
On the other hand, nobody knows if Manning can fully recover from a neck injury that forced him to undergo three surgeries. He'll turn 36 in March, so it might not be a safe bet to stick with the third-leading passer in NFL history.
There's always the option of trading away that No. 1 overall pick, too, as it would bring about a serious bounty for the Colts to replenish their roster.