Week 2 of the NFL season featured plenty of injuries to important players, and that could have a noticeable impact on the Week 3 spreads.
Running backs were hit particularly hard, which will cause concerns for fantasy football owners. For bettors, though, these injuries certainly are something to keep watch.
One game of note is the New England Patriots hosting the Houston Texans as home underdogs for the first time since their Super Bowl-winning 2014 season.
Here are the early spreads for all 16 Week 3 games, per OddsShark.
Thursday, Sept. 22
Houston Texans at New England Patriots (+2)
Sunday, Sept. 25
Baltimore Ravens at Jacksonville Jaguars (even)
Washington Redskins at New York Giants (-4)
Arizona Cardinals at Buffalo Bills (+5.5)
Denver Broncos at Cincinnati Bengals (-3.5)
Cleveland Browns at Miami Dolphins (-7)
Oakland Raiders at Tennessee Titans (even)
Minnesota Vikings at Carolina Panthers (-6.5)
Detroit Lions at Green Bay Packers (-8)
San Francisco 49ers at Seattle Seahawks (-11)
Los Angeles Rams at Tampa Bay Buccaneers (-3.5)
Pittsburgh Steelers at Philadelphia Eagles (+5.5)
San Diego Chargers at Indianapolis Colts (-3)
New York Jets at Kansas City Chiefs (-4)
Chicago Bears at Dallas Cowboys (-4)
Monday, Sept. 26
Atlanta Falcons at New Orleans Saints (-3.5)
Thumbnail photo via Matt Kartozian/USA TODAY Sports Images