Saints Vs. Giants: Betting Line, Predictions For NFL Week 2 Game

Editor’s note: NESN.com’s Mike Cole, Ricky Doyle and Andre Khatchaturian deliver their NFL picks every Thursday of the season, and here’s who they like in Sunday’s New Orleans Saints-New York Giants Week 2 game.

SUNDAY, SEPT. 18
New Orleans Saints (0-1) at (-4.5) New York Giants (1-0), 1 p.m.
Mike: Giants. The Saints struggle on the road — they’ve lost their last seven September road games as underdogs, 3-4 against the spread — and their defense still can’t stop a nosebleed. Like the Giants but love the over (52) here.
Ricky: Giants. The spread’s a little high, especially with the Giants barely squeaking by a rookie-led Cowboys team in their season opener. But with Victor Cruz healthy and second-round draft pick Sterling Shepard flashing his potential in Week 1, Eli Manning has a couple of viable weapons to take pressure off Odell Beckham Jr. That’s huge, given the Saints’ defensive issues.
Andre: Giants. Eli Manning and Drew Brees combined for 13 touchdowns last season when these two teams met. The difference now is that the Giants have an improved defense. The G-Men held Dak Prescott to 14-of-33 passing after he started 11 of 12. They should find a way to contain Brees late and win.