NFL Picks Week 4: Colts Vs. Jaguars Odds, Analysis, Predictions

Editor’s note: NESN.com’s Mike Cole, Ricky Doyle and Andre Khatchaturian deliver their NFL picks every Thursday of the season, and here’s who they like in the Indianapolis Colts-Jacksonville Jaguars Week 4 game, with the line from OddsShark.

(-2.5) Indianapolis Colts (1-2) vs. Jacksonville Jaguars (0-3), 9:30 a.m. (in London)
Mike: Colts. The Jaguars have lost two of three in London, and they almost squandered a huge lead against Buffalo across the pond last season. Indy’s not great, but it won’t let Jacksonville off the hook.
Ricky: Jaguars. The Jags have done the whole London thing before, so they should have an advantage, right? Gus Bradley sure hopes so, with Jacksonville underachieving at 0-3. An NFL head coach has been fired each of the last two seasons after losing in London in Week 4, so who’s to say the Jaguars won’t show Bradley the door without a win across the pond Sunday?
Andre: Jaguars. These are two mistake-prone quarterbacks who can carry the team on their backs. But the difference is defense. Despite being winless, I (somehow) still like what the Jaguars have done defensively (allowing five yards per play, eighth in the NFL). The Jags are better than their record shows, and having experience playing in London will help.