Dustin PedroiaThe Boston Red Sox hope to overcome dropping three of four to the New York Yankees when they face the Chicago White Sox on Tuesday night, but they’ll have to do so without Dustin Pedroia.

The Red Sox’s second baseman will miss his second consecutive game following a diagnosis of inflammation in his left wrist. The Boston Globe’s Nick Cafardo reported that Pedroia received a cortisone shot and hopes to return to the lineup Wednesday night.

Pedroia spoke to ESPN Boston’s Gordon Edes about the injury, which happened when he was sliding into second on a play during the Red Sox’s home opener.

“I just got caught in a weird angle when I was taken out,” Pedroia said. “Everything was inflamed, and you keep swinging and playing, it just adds up until you think something is really wrong. I landed kind of awkwardly. I thought it was general soreness from the rehab, but the more I swung, I kept feeling weaker and aching, things like that.”

Jonathan Herrera once again will start at second base in Pedroia’s absence.

Right-hander Jake Peavy is returning to U.S. Cellular Field for the first time since being traded from the White Sox to the Red Sox last season. Both games that Peavy started this season were no-decisions, so he’s looking to pick up his first win. He has a 2.13 ERA and 12 strikeouts over 12 2/3 innings.

Check out the lineups for both teams below.

Boston Red Sox (5-8)
Grady Sizemore, LF
Xander Bogaerts, SS
David Ortiz, DH
Mike Napoli, 1B
Daniel Nava, RF
A.J. Pierzynski, C
Ryan Roberts, 3B
Jackie Bradley Jr., CF
Jonathan Herrera, 2B

Jake Peavy RHP

Chicago White Sox (7-6)
Adam Eaton, CF
Marcus Semien, 2B
Conor Gillaspie, 3B
Jose Abreu, 1B
Adam Dunn, DH
Dayan Viciedo, RF
Alejandro De Aza, LF
Alexei Ramirez, SS
Tyler Flowers, C

Erik Johnson, RHP