The Boston Bruins have a difficult three-game stretch over the next four days, and it starts on the road Friday night against the Columbus Blue Jackets.

Boston will be without second-line left winger Brad Marchand, who’s dealing with an undisclosed ailment and didn’t travel with the team. It’s also possible that defenseman Kevan Miller could enter the lineup for the first time since he dislocated his right shoulder Oct. 18.

The Blue Jackets entered this season with high expectations after a competitive first-round loss to the Pittsburgh Penguins in the 2014 Stanley Cup playoffs. But they’ve arguably been hurt more by injuries than any other NHL team this campaign — even Boston. A number of forwards, defensemen and goalies have missed games because of injuries, which is one reason why the Blue Jackets sit at the bottom of the NHL Metropolitan Division standings.

Columbus is 2-7-1 in its last 10 games and lost 5-0 to the Detroit Red Wings on Tuesday night. However, the Blue Jackets’ blue line will receive a boost Friday.

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Here are the expected lines, pairings and starting goaltenders for Friday’s game.

BOSTON BRUINS (12-8-0, fourth in Atlantic)
Milan Lucic-David Krejci-Seth Griffith
Matt Fraser-Patrice Bergeron-Reilly Smith
Chris Kelly-Carl Soderberg-Loui Eriksson
Daniel Paille-Gregory Campbell-Simon Gagne

Dennis Seidenberg-Dougie Hamilton
Matt Bartkowski-Torey Krug
Joe Morrow-Kevan Miller/Zach Trotman

Niklas Svedberg (B’s haven’t made an official goaltender announcement)

COLUMBUS BLUE JACKETS (6-11-1, eighth in Metropolitan)
Boone Jenner-Ryan Johansen-Nick Foligno
Scott Hartnell-Artem Anisimov-Cam Atkinson
Matt Calvert-Alexander Wennberg-Jack Skille
Brian Gibbons-Adam Cracknell-Jared Boll

Dalton Prout-Jack Johnson
Jordan Leopold-David Savard
Kevin Connauton-James Wisniewski

Sergei Bobrovsky

Photo via Jay LaPrete/Associated Press