The New England Patriots host the Detroit Lions in a Week 12 inter-conference matchup of division leaders. The Patriots’ line is hanging between a touchdown and 7.5 points at sportsbooks monitored by The point total is set at 48 points.

The OddsShark Computer predicts a 33-25 Patriots win. This would result in a Patriots cover and hit the OVER. It would give the Patriots seven consecutive wins straight up, and their sixth in seven games against the spread.

The biggest line changes belong to Green Bay-Minnesota and Washington-San Francisco. Green Bay opened as a 7.5-point favorite, but the line now is sitting at 9.5 or 10 points. Green Bay is 5-2 ATS in the last seven matchups between these two teams, and the computer predicts the Packers cover with a 34-20 victory.

San Francisco also opened as a 7.5-point favorite, but the line has climbed to either nine or 10 points, depending on the sportsbook you choose. The 49ers are 1-3 ATS in their new home, while the Redskins are 2-3 ATS on the road. The computer predicts the Washington cover, with San Francisco winning 22-17.

The closest line remains Cincinnati-Houston. Originally a pick ’em, Houston currently is a one-point favorite. The Texans have won the last five SU and ATS, and the computer predicts another win, 25-22.

Indianapolis remains the biggest favorite, with a 14-point spread over Jacksonville, while Philadelphia is behind the Colts as an 11-point favorite over Tennessee. Both Indianapolis and Philadelphia are 4-6 ATS in their last 10 games as double-digit favorites. The computer predicts both will cover Sunday, with the Colts winning 31-13 and the Eagles winning 29-16.

The tough call of the day will be the Buffalo Bills and New York Jets. The Bills are field goal favorites, but the game is being moved because of snow in Buffalo. The line will likely adjust with the neutral field.

Sunday wraps up with an NFC East showdown between the Dallas Cowboys and New York Giants. Dallas is a field goal favorite on the road on the Week 12 NFL betting lines. The Giants have dropped five in a row against the spread, while the Cowboys have won six of nine against the spread. The computer predicts another Dallas cover, with a 28-18 final score.

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