College Football Week 2 Picks, Predictions Against Spread For Top 25 Games

The NFL started Thursday night with the New England Patriots and Kansas City Chiefs opening Week 1, but college football already is well underway.

Week 2 of the 2017 college football season kicks off Friday night, but Saturday has some really enticing matchups. The best of the bunch is No. 7 Oklahoma going on the road to play No. 2 Ohio State in a game of potential College Football Playoff participants.

Every week, NESN.com’s Nick Goss, Josh Schrock and Cam McDonough will pick every Top 25 matchup against the spread. All lines are from MyBookie.ag.

Standings After Week 1
Nick: 11-9-1
Cam: 10-10-1
Josh: 12-8-1

Friday, Sept. 8
No. 11 Oklahoma State (-28) at South Alabama
Nick: Oklahoma State
Cam: Oklahoma State
Josh: Oklahoma State

Saturday, Sept. 9
Cincinnati at No. 8 Michigan (-34.5)
Nick: Michigan
Cam: Cincinnati
Josh: Michigan

Florida Atlantic at No. 9 Wisconsin (-31.5)
Nick: Wisconsin
Cam: Wisconsin
Josh: Wisconsin

Charlotte at No. 19 Kansas State (-36.5)
Nick: Charlotte
Cam: Charlotte
Josh: Charlotte

Fresno State at No. 1 Alabama (-44)
Nick: Fresno State
Cam: Alabama
Josh: Alabama

Pittsburgh at No. 4 Penn State (-21)
Nick: Penn State
Cam: Pittsburgh
Josh: Penn State

Delaware at No. 18 Virginia Tech (no line)
Nick: V-Tech
Cam: V-Tech
Josh: V-Tech

No. 23 TCU (-3) at Arkansas
Nick: TCU
Cam: Arkansas
Josh: Arkansas

Indiana State at No. 25 Tennessee (no line)
Nick: Tennessee
Cam: Tennessee
Josh: Tennessee

No. 13 Auburn at No. 3 Clemson (-5)
Nick: Clemson
Cam: Clemson
Josh: Auburn

No. 5 Oklahoma at No. 2 Ohio State (-7.5)
Nick: Ohio State
Cam: Ohio State
Josh: Ohio State

No. 15 Georgia at No. 24 Notre Dame (-4)
Nick: Georgia
Cam: Georgia
Josh: Georgia

No. 14 Stanford at No. 6 USC (-6)
Nick: Stanford
Cam: Stanford
Josh: Stanford

Boise State at No. 20 Washington State (-10.5)
Nick: Washington State
Cam: Washington State
Josh: Washington State

Thumbnail photo via Charles LeClaire/USA TODAY Sports Images