A long list of injuries always piles up by the end of any NFL Sunday, but Week 5 was particularly tough for some star players.

New York Giants wide receiver Odell Beckham Jr. fractured his ankle, while Houston Texans defensive end J.J. Watt suffered another gruesome injury with a reported tibial plateau fracture. Both injuries could be season-ending for the NFL stars and devastating blows to their teams, fans and the league as a whole.

NESN.com’s Courtney Cox has all the details in the video above, presented by Bedgear.

Thumbnail photo via Robert Deutsch and Troy Taormina/USA TODAY Sports Images