Mark Ingram crashed his car into an 18-wheeler in Huntsville, Ala., on Friday morning, according to a report by WBRC Fox 6.
Ingram was driving with his girlfriend shortly before 1 a.m. There were no reported injuries.
The report said that alcohol was not a factor, but police wouldn't say who was at fault for the accident.
Ingram, 21, was selected with the 28th pick of April's NFL draft by the New Orleans Saints after a standout career at Alabama, where he won the Heisman Trophy in 2009 and the BCS Championship in 2010.
Ingram was signing autographs and taking photos with fans earlier in the night with former college teammate Julio Jones, now of the Atlanta Falcons.