The start will be Gonzalez's eighth in the outfield this season. He'll be hitting third again in the batting order, just behind Mike Aviles who will be hitting in the second slot for the first time this year.
Boston batters are up against a tough challenge with Tigers lefty Drew Smyly (2-1, 3.14) taking the mound in hopes of pulling out Detroit's first win of this four-game set at Fenway. Jon Lester (3-4, 4.72) gets the start on the bump for the Red Sox, hoping to rebound from his rough outing against the Rays over the weekend.
Take a peek at the lineups for both teams, below.
Red Sox (25-24)
Daniel Nava, LF
Mike Aviles, SS
Adrian Gonzalez, RF
David Ortiz, DH
Kevin Youkilis, 1B
Will Middlebrooks, 3B
Marlon Byrd, CF
Kelly Shoppach, C
Nick Punto, 2B
Jon Lester, LHP
Tigers (23-26)
Quinton Berry, CF
Danny Worth, 2B
Miguel Cabrera, 3B
Prince Fielder, 1B
Delmon Young, LF
Brandon Boesch, RF
Jhonny Peralta, SS
Alex Avila, C
Gerald Laird, DH
Drew Smyly, LHP