Patriots Injuries: How Jerod Mayo Assessed Key Departures

Things went from bad to worse for the New England Patriots at Levi's Stadium on Sunday afternoon.

The Patriots suffered three crucial injuries with captain David Andrews (shoulder), safety Kyle Dugger (ankle) and offensive tackle Caedan Wallace (ankle) all exiting the game and not returning. Andrews played a mere one offensive series in the 30-13 loss to the San Francisco 49ers.

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Patriots head coach Jerod Mayo spoke about New England's injuries, but told reporters he would know more Monday.

"We sustained a few injuries to some warriors out there today," Mayo told reporters, per a team-provided video. "Some big injuries -- big as far as who it was. Those guys will come in tomorrow and do their injury check. I'm not sure how serious or not serious the injuries are with those guys. But those guys that couldn't finish the game, obviously, are a big part of what we do."

New England has faced some tough injury luck through four games. Offensive tackle Vederian Lowe has not played since Week 2 and linebacker Ja'Whaun Bentley was placed on injured reserve after a pectoral injury. That's in addition to Christian Barmore, who was hospitalized with blood clots at the beginning of training camp.