UPDATE (9:19 p.m. ET): Isaiah Wynn has returned for the New England Patriots, missing just one offensive drive with an ankle injury.
The Patriots left tackle was sidelined on New England's second offensive possession.
(ORIGINAL STORY): Isaiah Wynn's night may not have lasted too long.
The New England Patriots left tackle, who was questionable entering "Monday Night Football" with an ankle injury, seems to have aggravated it early in the second quarter against the New York Jets.
Wynn left the game on New England's second possession, and has been deemed "questionable to return," according to the team.
Korey Cunningham, the lone available offensive lineman, replaced Wynn on third down of the Patriots' second offensive drive.