Week 5 of the 2015 NFL season kicks off Thursday night with the Houston Texans hosting the Indianapolis Colts.

The Texans were expected to challenge the Colts for the AFC South division crown, but Houston has disappointed through the first quarter of the season with a 1-3 record. Another loss could severely decrease their chances of winning the division.

The Colts, meanwhile, could be without starting quarterback Andrew Luck for a second straight week. He’s officially questionable with a shoulder injury.

When: Thursday, Oct. 8 at 8:30 p.m. ET
Watch: NFL Network Online

Thumbnail photo via Timothy T. Ludwig/USA TODAY Sports Images

Thumbnail photo via Sep 13, 2015; Orchard Park, NY, USA; Indianapolis Colts quarterback Andrew Luck (12) looks to throw a pass during the second half against the Buffalo Bills at Ralph Wilson Stadium.