College Football Week 3 Picks, Predictions Against Spread For Top 25 Teams

Week 2 of the college football season didn’t feature many highly anticipated games.

That changes in Week 3, which has four games featuring two Top 25 teams. The two best are No. 2 Florida State at No. 10 Louisville, and No. 12 Michigan State visiting No. 18 Notre Dame.

Here are my predictions for Week 3 of the 2016 college football season. All spreads are from OddsShark, and my picks are italicized.

Season picks record: 29-12-1 (17-5-1 last week)

Thursday, Sept. 15
No. 6 Houston (-7.5) at Cincinnati

Friday, Sept. 16
No. 21 Baylor (-30.5) at Rice

Saturday, Sept. 17
Ohio at No. 15 Tennessee (-27)
South Carolina State at No. 5 Clemson (no line)
No. 2 Florida State (-2) at No. 10 Louisville
North Dakota State at No. 13 Iowa (no line)
Georgia State at No. 9 Wisconsin (-34)
No. 25 Miami (-3.5) at Appalachian State
Colorado at No. 4 Michigan (-20.5)
No. 1 Alabama (-11) at No. 19 Ole Miss
Mississippi State at No. 20 LSU (-14)
No. 17 Texas A&M (+3.5) at Auburn
Texas State at No. 24 Arkansas (-31)
North Texas at No. 23 Florida (-36.5)
No. 12 Michigan State at No. 18 Notre Dame (-7.5)
No. 16 Georgia (-6.5) at Missouri
No. 3 Ohio State at No. 14 Oklahoma (+1.5)
USC at No. 7 Stanford (-9)
Portland State at No. 8 Washington (no line)
No. 11 Texas (-8) at California