College Football Week 1 Picks, Predictions Against Spread For Top 25 Games

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College football got underway last weekend, but the Labor Day weekend is when the sport really kicks off with a plethora of fantastic matchups, many of them including Top 25 ranked teams.

The most-anticipated games are, of course, No. 11 Michigan vs. No. 17 Florida and No. 3 Florida State vs. No. 1 Alabama. The Seminoles vs. Crimson Tide matchup might actually be the best opening week game in the sport’s history.

Every week, NESN.com’s Nick Goss, Josh Schrock and Cam McDonough will pick every Top 25 matchup against the spread. As always, all lines are provided by OddsShark.

Thursday, Aug. 31
Tulsa at No. 10 Oklahoma State (-18.5)
Nick: Oklahoma State
Cam: Tulsa
Josh: Oklahoma State

No. 2 Ohio State (-21.5) at Indiana
Nick: Indiana
Cam: Ohio State
Josh: Ohio State

Friday, Sept. 1
Utah State at No. 9 Wisconsin (-27.5)
Nick: Wisconsin
Cam: Utah State
Josh: Utah State

No. 8 Washington (-27.5) at Rutgers
Nick: Washington
Cam: Washington
Josh: Washington

Saturday, Sept. 2
Kent State at No. 5 Clemson (-40)
Nick: Kent State
Cam: Kent State
Josh: Kent State

Akron at No. 6 Penn State (-31)
Nick: Akron
Cam: Penn State
Josh: Penn State

Maryland at No. 23 Texas (-18.5)
Nick: Texas
Cam: Maryland
Josh: Texas

Bethune Cookman at No. 18 Miami (no line)
Nick: Miami
Cam: Miami
Josh: Miami

UTEP at No. 7 Oklahoma (-43)
Nick: UTEP
Cam: UTEP
Josh: Oklahoma

No. 11 Michigan (-4) at No. 17 Florida
Nick: Michigan
Cam: Michigan
Josh: Michigan

Stony Brook at No. 19 South Florida (no line)
Nick: South Florida
Cam: South Florida
Josh: South Florida

Western Michigan at No. 4 USC (-27.5)
Nick: USC
Cam: USC
Josh: USC

Appalachian State at No. 15 Georgia (-14.5)
Nick: Georgia
Cam: Appalachian State
Josh: Appalachian State

Central Arkansas at No. 20 Kansas State (no line)
Nick: Kansas State
Cam: Kansas State
Josh: Kansas State

Georgia Southern at No. 12 Auburn (-34)
Nick: Georgia Southern
Cam: Georgia Southern
Josh: Auburn

No. 16 Louisville (-24.5) at Purdue
Nick: Louisville
Cam: Louisville
Josh: Louisville

No. 3 Florida State vs. No. 1 Alabama (-7)
Nick: Alabama
Cam: Florida State
Josh: Florida State

BYU at No. 13 LSU (-14.5)
Nick: LSU
Cam: BYU
Josh: LSU

Montana State at No. 24 Washington State (no line)
Nick: Washington State
Cam: Washington State
Josh: Washington State

Sunday, Sept. 3
No. 22 West Virginia at No. 21 Virginia Tech (-4.5)
Nick: Virginia Tech
Cam: Virginia Tech
Josh: Virginia Tech

Monday, Sept. 4
No. 25 Tennessee (-3) at Georgia Tech
Nick: Tennessee
Cam: Georgia Tech
Josh: Tennessee

Thumbnail photo via Mickey Welsh/Montgomery Advertiser via USA TODAY Sports Images

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