Red Sox captain Jason Varitek will get his first start of the season as the Sox take on the Indians on Wednesday night.
As for the rest of manager Terry Francona's lineup, things remain as they were prior to Tuesday night's series opener in Cleveland, as Carl Crawford (2-for-15) stays in the No. 2 hole and Dustin Pedroia (5-for-15) will once again bat third in front of Adrian Gonzalez (5-for-17).
Catcher Jarrod Saltalamacchia gets his first day off after going 1-for-11 in the first four games of the season.
Here are the lineups for both teams:
Boston
Jacoby Ellsbury, CF
Carl Crawford, LF
Dustin Pedroia, 2B
Adrian Gonzalez, 1B
Kevin Youkilis, 3B
David Ortiz, DH
J.D. Drew, RF
Jason Varitek, C
Marco Scutaro, SS
Cleveland
Michael Brantley, CF
Asdrubal Cabrera, SS
Shin-Soo Choo, RF
Carlos Santana, C
Travis Hafner, DH
Orlando Cabrera, 2B
Travis Buck, LF
Matt LaPorta, 1B
Jack Hannahan, 3B
