NFL Week 1 Schedule: Early Point Spreads For Each Season-Opening Game

The Buccaneers and Cowboys will kick off the 2021 campaign


May 12, 2021

The NFL on Wednesday morning released its full Week 1 schedule for the 2021 season.

Tom Brady and the defending Super Bowl champion Tampa Bay Buccaneers will kick off the slate by hosting the Dallas Cowboys at Raymond James Stadium on Thursday, Sept. 9, at 8:20 p.m. ET.

The first “Sunday Night Football” game of the new campaign will feature the Chicago Bears traveling to SoFi Stadium for a date with the Los Angeles Rams, while the first “Monday Night Football” showdown will see the Las Vegas Raiders host the Baltimore Ravens at Allegiant Stadium.

The other 13 games on the season-opening docket — nine at 1 p.m. ET and four at 4:25 p.m. ET on Sunday, Sept. 12 — will carry varying levels of intrigue.

Sam Darnold, now quarterback of the Carolina Panthers, will face his former team, the New York Jets, who just drafted QB Zach Wilson with the No. 2 pick in the 2021 NFL Draft.

Trevor Lawrence, the No. 1 overall selection, will begin his NFL career against the Houston Texans, provided the rookie signal-caller starts for the Jacksonville Jaguars in Week 1.

Baker Mayfield and the Cleveland Browns will face Patrick Mahomes and the Kansas City Chiefs in a 2020 divisional-round playoff rematch at Arrowhead Stadium.

All in all, it should be fun.

The Week 1 schedule — released ahead of the full-season reveal Wednesday night — is below, along with early point spreads provided via consensus data.

Dallas Cowboys at Tampa Bay Buccaneers (-6.5), 8:20 p.m. ET

Jacksonville Jaguars (-1.5) at Houston Texans, 1 p.m. ET

Pittsburgh Steelers at Buffalo Bills (-6.5), 1 p.m. ET

New York Jets at Carolina Panthers (-4.5), 1 p.m. ET

Arizona Cardinals at Tennessee Titans (-2.5), 1 p.m. ET

Los Angeles Chargers (-1.5) at Washington Football Team, 1 p.m. ET

Minnesota Vikings (-2.5) at Cincinnati Bengals, 1 p.m. ET

San Francisco 49ers (-7.5) at Detroit Lions, 1 p.m. ET

Philadelphia Eagles at Atlanta Falcons (-3.5), 1 p.m. ET

Seattle Seahawks at Indianapolis Colts (-2.5), 1 p.m. ET

Cleveland Browns at Kansas City Chiefs (-5.5), 4:25 p.m. ET

Miami Dolphins at New England Patriots (-2), 4:25 p.m. ET

Denver Broncos (-1.5) at New York Giants, 4:25 p.m. ET

Green Bay Packers at New Orleans Saints (OFF), 4:25 p.m. ET

Chicago Bears at Los Angeles Rams (-7), 8:20 p.m. ET

Baltimore Ravens (-6) at Las Vegas Raiders, 8:15 p.m. ET

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